The broad scope of the book allows the side-by-side treatment of specialized methods with basic biochemical techniques for the isolation, characterization and functional analysis of RNA. All pertinent laboratory methods are presented in detail, including
+ RNA synthesis, modification and ligation
+ Sequence and structure determination of RNA
+ Isolation and purification of ribonucleoproteins
+ RNA crystallization
+ Single molecule studies on RNA
+ Analysis of splice variants
+ RNA imaging in vivo
+ Modeling and prediction of RNA structure
+ RNA microarrays
+ Aptamer libraries and SELEX technology
+ RNA interference
In short, a guide to successful experimentation for molecular biologists, biochemists and biotechnologists and of interest to every researcher experimenting with RNA
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